Sachio Morimoto Selected Research

Propyl Gallate

7/2014	In vivo effects of propyl gallate, a novel Ca(2+) sensitizer, in a mouse model of dilated cardiomyopathy caused by cardiac troponin T mutation.
3/2009	Propyl gallate, a strong antioxidant, increases the Ca2+ sensitivity of cardiac myofilament.

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Sachio Morimoto Research Topics

Disease

19	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2021 - 01/2002
16	Heart Failure 01/2022 - 01/2005
8	Cardiomyopathies (Cardiomyopathy) 01/2019 - 01/2007
7	Neoplasms (Cancer) 04/2015 - 12/2005
5	Fibrosis (Cirrhosis) 01/2021 - 10/2014
4	familial dilated cardiomyopathy 01/2016 - 07/2007
4	Restrictive Cardiomyopathy 12/2014 - 12/2005
4	Colonic Neoplasms (Colon Cancer) 01/2013 - 05/2007
3	Cardiac Arrhythmias (Arrythmia) 01/2018 - 01/2012
3	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2018 - 10/2009
3	Cardiomegaly (Heart Hypertrophy) 02/2017 - 07/2007
3	Heart Diseases (Heart Disease) 02/2017 - 10/2009
3	Body Weight (Weight, Body) 10/2014 - 07/2011
2	Sudden Death 05/2015 - 07/2007
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 03/2013 - 12/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 11/2010 - 08/2009
2	Atherosclerosis 01/2009 - 10/2008
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 12/2005 - 11/2005
2	Keloid 08/2004 - 11/2002
1	Inflammation (Inflammations) 01/2021
1	Familial Hypertrophic Cardiomyopathy (Cardiomyopathy, Familial Hypertrophic) 01/2018
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 02/2017
1	Ventricular Remodeling 02/2017
1	Endocardial Cushion Defects 01/2016
1	Muscular Diseases (Myopathy) 07/2015
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2014
1	Cardiotoxicity 10/2014
1	Atrial Remodeling 01/2014
1	Hyperthyroidism 09/2010
1	Left Ventricular Dysfunction 04/2010
1	Ventricular Fibrillation 10/2009

Drug/Important Bio-Agent (IBA)

10	Troponin T (Troponin T1)IBA 01/2021 - 12/2003
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2007
7	CateninsIBA 07/2015 - 09/2010
6	TroponinIBA 01/2017 - 01/2002
5	Celecoxib (Celebrex)FDA Link 02/2017 - 05/2007
4	Cyclin D1IBA 06/2014 - 11/2005
3	Troponin IIBA 07/2013 - 12/2005
2	Pharmaceutical PreparationsIBA 11/2020 - 09/2010
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 10/2014
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2019 - 01/2018
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 02/2017 - 06/2007
2	2,5-dimethylcelecoxibIBA 02/2017 - 07/2011
2	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2016 - 07/2011
2	pimobendanIBA 05/2015 - 07/2007
2	Brain Natriuretic Peptide (Natrecor)FDA Link 10/2014 - 07/2011
2	Propyl GallateIBA 07/2014 - 03/2009
2	Therapeutic UsesIBA 07/2014 - 10/2009
2	trans-crotonin (CTN)IBA 03/2013 - 07/2007
2	Sch 00013IBA 04/2010 - 01/2005
2	LipocalinsIBA 01/2009 - 10/2008
2	prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA 01/2009 - 10/2008
2	StaurosporineIBA 08/2004 - 11/2002
1	GTP-Binding Proteins (G-Protein)IBA 01/2022
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2021
1	CC ChemokinesIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Amino Acids FDA Link 01/2021
1	ArrestinIBA 11/2020
1	Sar-Arg-Val-Tyr-Ile-His-Pro-Ala-OHIBA 11/2020
1	NF-kappa B (NF-kB)IBA 01/2019
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 01/2018
1	fasudil (AT 877)IBA 01/2018
1	Trinitrotoluene (TNT)IBA 01/2018
1	Myosin-Light-Chain PhosphataseIBA 01/2018
1	rho-Associated KinasesIBA 01/2018
1	Thrombin FDA Link 02/2017
1	Glycogen Synthase (Synthase I)IBA 02/2017
1	Glycogen Synthase Kinase 3IBA 02/2017
1	Protein Isoforms (Isoforms)IBA 01/2016
1	ConnexinsIBA 01/2016
1	GhrelinIBA 10/2014
1	QuercetinIBA 10/2014
1	DNA (Deoxyribonucleic Acid)IBA 10/2014
1	Transcription Factors (Transcription Factor)IBA 06/2014
1	candesartanIBA 01/2014
1	Angiotensin Receptor AntagonistsIBA 01/2014
1	Adenosine Triphosphatases (ATPase)IBA 03/2013
1	HemosiderinIBA 01/2013
1	Serotonin (5 Hydroxytryptamine)IBA 12/2012
1	Ion Channels (Ion Channel)IBA 01/2012
1	TeaIBA 11/2010
1	PolyphenolsIBA 11/2010
1	matrigelIBA 09/2010
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2010
1	Thyroid HormonesIBA 09/2010
1	Iodide Peroxidase (Deiodinase)IBA 09/2010
1	Phosphotransferases (Kinase)IBA 08/2010
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 08/2010
1	Lysine (L-Lysine)FDA Link 05/2010
1	CalciumIBA 04/2010
1	Metoprolol (Toprol-XL)FDA LinkGeneric 10/2009
1	Adrenergic Receptors (Adrenergic Receptor)IBA 10/2009
1	AldosteroneIBA 08/2009
1	Eplerenone (Inspra)FDA LinkGeneric 08/2009
1	AntioxidantsIBA 03/2009
1	CytokinesIBA 01/2009

Therapy/Procedure

3	Therapeutics 12/2014 - 08/2004
2	Oral Administration 04/2015 - 06/2014
2	Drug Therapy (Chemotherapy) 10/2014 - 09/2010